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Functional Profile of CD8(+) T-Cells in Response to HLA-A*02:01-Restricted Mutated Epitopes Derived from the Gag Protein of Circulating HIV-1 Strains from Medellín, Colombia

CD8(+) T-cells play a crucial role in the control of HIV replication. HIV-specific CD8(+) T-cell responses rapidly expand since the acute phase of the infection, and it has been observed that HIV controllers harbor CD8(+) T-cells with potent anti-HIV capacity. The development of CD8(+) T-cell-based...

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Detalles Bibliográficos
Autores principales: Sánchez-Martínez, Alexandra, Acevedo-Sáenz, Liliana, Alzate-Ángel, Juan Carlos, Álvarez, Cristian M., Guzmán, Fanny, Roman, Tanya, Urcuqui-Inchima, Silvio, Cardona-Maya, Walter D., Velilla, Paula Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980466/
https://www.ncbi.nlm.nih.gov/pubmed/35392101
http://dx.doi.org/10.3389/fimmu.2022.793982