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Exploring the glycosylation of mucins by use of O-glycodomain reporters recombinantly expressed in glycoengineered HEK293 cells

Mucins and glycoproteins with mucin-like regions contain densely O-glycosylated domains often found in tandem repeat (TR) sequences. These O-glycodomains have traditionally been difficult to characterize because of their resistance to proteolytic digestion, and knowledge of the precise positions of...

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Detalles Bibliográficos
Autores principales: Konstantinidi, Andriana, Nason, Rebecca, Čaval, Tomislav, Sun, Lingbo, Sørensen, Daniel M., Furukawa, Sanae, Ye, Zilu, Vincentelli, Renaud, Narimatsu, Yoshiki, Vakhrushev, Sergey Y., Clausen, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980628/
https://www.ncbi.nlm.nih.gov/pubmed/35247390
http://dx.doi.org/10.1016/j.jbc.2022.101784