CAR T cell therapy and the tumor microenvironment: Current challenges and opportunities

Chimeric antigen receptor (CAR) T cell therapy has demonstrated remarkable outcomes in individuals with hematological malignancies, but its success has been hindered by barriers intrinsic to the tumor microenvironment (TME), particularly for solid tumors, where it has yet to make its mark. In this a...

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Detalles Bibliográficos
Autores principales: Kankeu Fonkoua, Lionel A., Sirpilla, Olivia, Sakemura, Reona, Siegler, Elizabeth L., Kenderian, Saad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980704/
https://www.ncbi.nlm.nih.gov/pubmed/35434273
http://dx.doi.org/10.1016/j.omto.2022.03.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980704/
https://www.ncbi.nlm.nih.gov/pubmed/35434273
http://dx.doi.org/10.1016/j.omto.2022.03.009

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