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Divergent Ca(2+)/calmodulin feedback regulation of Ca(V)1 and Ca(V)2 voltage-gated calcium channels evolved in the common ancestor of Placozoa and Bilateria

Ca(V)1 and Ca(V)2 voltage-gated calcium channels evolved from an ancestral Ca(V)1/2 channel via gene duplication somewhere near the stem animal lineage. The divergence of these channel types led to distinguishing functional properties that are conserved among vertebrates and bilaterian invertebrates...

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Detalles Bibliográficos
Autores principales: Gauberg, Julia, Elkhatib, Wassim, Smith, Carolyn L., Singh, Anhadvir, Senatore, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980814/
https://www.ncbi.nlm.nih.gov/pubmed/35182524
http://dx.doi.org/10.1016/j.jbc.2022.101741