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miR-374a-5p regulates inflammatory genes and monocyte function in patients with inflammatory bowel disease

MicroRNAs are critical regulators of gene expression controlling cellular processes including inflammation. We explored their role in the pathogenesis of inflammatory bowel disease (IBD) and identified reduced expression of miR-374a-5p in IBD monocytes that correlated with a module of up-regulated g...

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Detalles Bibliográficos
Autores principales: Perez-Sanchez, Carlos, Barbera Betancourt, Ariana, Lyons, Paul A., Zhang, Zinan, Suo, Chenqu, Lee, James C., McKinney, Eoin F., Modis, Louise K., Ellson, Christian, Smith, Kenneth G.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980842/
https://www.ncbi.nlm.nih.gov/pubmed/35363256
http://dx.doi.org/10.1084/jem.20211366