FNDC5 Causes Resistance to Sorafenib by Activating the PI3K/Akt/Nrf2 Pathway in Hepatocellular Carcinoma Cells

In this study, we aimed to reveal the resistance mechanism of hepatocellular carcinoma (HCC) cells to sorafenib by exploring the effect of FNDC5 on sorafenib-induced ferroptosis in HCC cells. We compared the expression level of FNDC5 between sorafenib-resistant and sorafenib-sensitive HCC cell lines...

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Detalles Bibliográficos
Autores principales: Liu, Huayuan, Zhao, Lei, Wang, Mengya, Yang, Kexin, Jin, Zhipeng, Zhao, Chengjian, Shi, Guangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980859/
https://www.ncbi.nlm.nih.gov/pubmed/35392237
http://dx.doi.org/10.3389/fonc.2022.852095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980859/
https://www.ncbi.nlm.nih.gov/pubmed/35392237
http://dx.doi.org/10.3389/fonc.2022.852095

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