CD44/ERM/F‐actin complex mediates targeted nuclear degranulation and excessive neutrophil extracellular trap formation during sepsis

Neutrophils release neutrophil extracellular traps (NETs) to capture and kill pathogens, but excessive NET release can damage the surrounding tissues. Myeloperoxidase (MPO) and neutrophil elastase (NE) are thought to be important in promoting histone depolymerization and DNA breakage in the nucleus....

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Detalles Bibliográficos
Autores principales: Shao, Yiming, Li, Linbin, Liu, Lu, Yang, Yunxi, Huang, Jiamin, Ji, Dongdong, Zhou, Yuying, Chen, Yi, Zhu, Zhechen, Sun, Bingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980940/
https://www.ncbi.nlm.nih.gov/pubmed/35146909
http://dx.doi.org/10.1111/jcmm.17231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980940/
https://www.ncbi.nlm.nih.gov/pubmed/35146909
http://dx.doi.org/10.1111/jcmm.17231

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