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CD44/ERM/F‐actin complex mediates targeted nuclear degranulation and excessive neutrophil extracellular trap formation during sepsis
Neutrophils release neutrophil extracellular traps (NETs) to capture and kill pathogens, but excessive NET release can damage the surrounding tissues. Myeloperoxidase (MPO) and neutrophil elastase (NE) are thought to be important in promoting histone depolymerization and DNA breakage in the nucleus....
Autores principales: | Shao, Yiming, Li, Linbin, Liu, Lu, Yang, Yunxi, Huang, Jiamin, Ji, Dongdong, Zhou, Yuying, Chen, Yi, Zhu, Zhechen, Sun, Bingwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980940/ https://www.ncbi.nlm.nih.gov/pubmed/35146909 http://dx.doi.org/10.1111/jcmm.17231 |
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