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NAD(+) ameliorates endotoxin‐induced acute kidney injury in a sirtuin1–dependent manner via GSK‐3β/Nrf2 signalling pathway

Acute kidney injury (AKI) is a substantial worldwide public health concern with no specific and effective therapies in clinic. NAD(+) is a pivotal determinant of cellular energy metabolism involved in the progression of AKI; however, its mechanism in kidney injury remains poorly understood. Sirtuin...

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Detalles Bibliográficos
Autores principales: He, Simeng, Gao, Qiaoying, Wu, Xiaoyang, Shi, Jia, Zhang, Yuan, Yang, Jing, Li, Xiangyun, Du, Shihan, Zhang, Yanfang, Yu, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980955/
https://www.ncbi.nlm.nih.gov/pubmed/35137552
http://dx.doi.org/10.1111/jcmm.17222