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A Novel Hierarchical Clustering Approach for Joint Analysis of Multiple Phenotypes Uncovers Obesity Variants Based on ARIC

Genome-wide association studies (GWASs) have successfully discovered numerous variants underlying various diseases. Generally, one-phenotype one-variant association study in GWASs is not efficient in identifying variants with weak effects, indicating that more signals have not been identified yet. N...

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Detalles Bibliográficos
Autores principales: Fu, Liwan, Wang, Yuquan, Li, Tingting, Yang, Siqian, Hu, Yue-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981031/
https://www.ncbi.nlm.nih.gov/pubmed/35391794
http://dx.doi.org/10.3389/fgene.2022.791920