The Acute Effects of Furosemide on Na-K-Cl Cotransporter-1, Fetuin-A and Pigment Epithelium-Derived Factor in the Guinea Pig Cochlea

BACKGROUND: Furosemide is a loop diuretic used to treat edema; however, it also targets the Na-K-Cl cotransporter-1 (NKCC1) in the inner ear. In very high doses, furosemide abolishes the endocochlear potential (EP). The aim of the study was to gain a deeper understanding of the temporal course of th...

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Detalles Bibliográficos
Autores principales: Edvardsson Rasmussen, Jesper, Lundström, Patrik, Eriksson, Per Olof, Rask-Andersen, Helge, Liu, Wei, Laurell, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981210/
https://www.ncbi.nlm.nih.gov/pubmed/35392272
http://dx.doi.org/10.3389/fnmol.2022.842132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981210/
https://www.ncbi.nlm.nih.gov/pubmed/35392272
http://dx.doi.org/10.3389/fnmol.2022.842132

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