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To go or not to go? Biological logic gating engineered T cells

Genetically engineered T cells have been successfully used in the treatment of hematological malignancies, greatly increasing both progression-free and overall survival in patients. However, the outcomes of patients treated with Chimeric Antigen Receptor (CAR) T cells targeting solid tumors have bee...

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Detalles Bibliográficos
Autores principales: Abbott, Rebecca C, Hughes-Parry, Hannah E, Jenkins, Misty R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981284/
https://www.ncbi.nlm.nih.gov/pubmed/35379738
http://dx.doi.org/10.1136/jitc-2021-004185