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To go or not to go? Biological logic gating engineered T cells
Genetically engineered T cells have been successfully used in the treatment of hematological malignancies, greatly increasing both progression-free and overall survival in patients. However, the outcomes of patients treated with Chimeric Antigen Receptor (CAR) T cells targeting solid tumors have bee...
Autores principales: | Abbott, Rebecca C, Hughes-Parry, Hannah E, Jenkins, Misty R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981284/ https://www.ncbi.nlm.nih.gov/pubmed/35379738 http://dx.doi.org/10.1136/jitc-2021-004185 |
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