Tracing the evolution of aneuploid cancers by multiregional sequencing with CRUST

Clonal deconvolution of mutational landscapes is crucial to understand the evolutionary dynamics of cancer. Two limiting factors for clonal deconvolution that have remained unresolved are variation in purity and chromosomal copy number across different samples of the same tumor. We developed a semi-...

Descripción completa

Detalles Bibliográficos
Autores principales: Chattopadhyay, Subhayan, Karlsson, Jenny, Valind, Anders, Andersson, Natalie, Gisselsson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Case Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981300/
https://www.ncbi.nlm.nih.gov/pubmed/34343239
http://dx.doi.org/10.1093/bib/bbab292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981300/
https://www.ncbi.nlm.nih.gov/pubmed/34343239
http://dx.doi.org/10.1093/bib/bbab292

Ejemplares similares