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Tracing the evolution of aneuploid cancers by multiregional sequencing with CRUST
Clonal deconvolution of mutational landscapes is crucial to understand the evolutionary dynamics of cancer. Two limiting factors for clonal deconvolution that have remained unresolved are variation in purity and chromosomal copy number across different samples of the same tumor. We developed a semi-...
Autores principales: | Chattopadhyay, Subhayan, Karlsson, Jenny, Valind, Anders, Andersson, Natalie, Gisselsson, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981300/ https://www.ncbi.nlm.nih.gov/pubmed/34343239 http://dx.doi.org/10.1093/bib/bbab292 |
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