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Untargeted 2D NMR Metabolomics of [(13)C-methyl]Methionine-Labeled Tumor Models Reveals the Non-DNA Methylome and Provides Clues to Methyl Metabolism Shift during Tumor Progression

[Image: see text] For more than a decade, DNA and histone methylations have been the focus of extensive work, although their relationship with methyl group metabolism was overlooked. Recently, it has emerged that epigenetic methylations are influenced by methyl donor nutrient availability, cellular...

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Detalles Bibliográficos
Autores principales: Morvan, Daniel, Cachin, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981308/
https://www.ncbi.nlm.nih.gov/pubmed/35196455
http://dx.doi.org/10.1021/acs.jproteome.1c00778