Catalytic Diastereo- and Enantioselective Synthesis of Tertiary Trifluoromethyl Carbinols through a Vinylogous Aldol Reaction of Alkylidenepyrazolones with Trifluoromethyl Ketones

[Image: see text] A diastereo- and enantioselective organocatalytic aldol reaction between alkylidenepyrazolones and trifluoromethyl ketones leading to chiral tertiary alcohols bearing a trifluoromethyl group is presented. The methodology is based on the use of a bifunctional organocatalyst in order...

Descripción completa

Detalles Bibliográficos
Autores principales: Carceller-Ferrer, Laura, González del Campo, Aleix, Vila, Carlos, Blay, Gonzalo, Muñoz, M. Carmen, Pedro, José R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981347/
https://www.ncbi.nlm.nih.gov/pubmed/35293756
http://dx.doi.org/10.1021/acs.joc.1c02817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981347/
https://www.ncbi.nlm.nih.gov/pubmed/35293756
http://dx.doi.org/10.1021/acs.joc.1c02817

Ejemplares similares