Progranulin promotes hippocampal neurogenesis and alleviates anxiety‐like behavior and cognitive impairment in adult mice subjected to cerebral ischemia

AIMS: Cerebral ischemia can lead to anxiety and cognitive impairment due to the loss of hippocampal neurons. Facilitation of endogenous neurogenesis in the hippocampus is a potential therapeutic strategy for alleviating ischemia‐induced anxiety and cognitive impairment. Progranulin (PGRN), a secreto...

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Detalles Bibliográficos
Autores principales: Sun, Siqi, Zhou, Jinlong, Li, Zhongqi, Wu, Yuzi, Wang, Hao, Zheng, Qi, Adu‐Nti, Frank, Fan, Juan, Tian, Yingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981488/
https://www.ncbi.nlm.nih.gov/pubmed/35146924
http://dx.doi.org/10.1111/cns.13810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981488/
https://www.ncbi.nlm.nih.gov/pubmed/35146924
http://dx.doi.org/10.1111/cns.13810

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