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UBIAD1 alleviates ferroptotic neuronal death by enhancing antioxidative capacity by cooperatively restoring impaired mitochondria and Golgi apparatus upon cerebral ischemic/reperfusion insult

BACKGROUND: Neuronal death due to over-oxidative stress responses defines the pathology of cerebral ischemic/reperfusion (I/R) insult. Ferroptosis is a form of oxidative cell death that is induced by disruption of the balance between antioxidants and pro-oxidants in cells. However, the potential mec...

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Detalles Bibliográficos
Autores principales: Huang, Yan, Liu, Jianyang, He, Jialin, Hu, Zhiping, Tan, Fengbo, Zhu, Xuelin, Yuan, Fulai, Jiang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981649/
https://www.ncbi.nlm.nih.gov/pubmed/35379328
http://dx.doi.org/10.1186/s13578-022-00776-9