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Systematic review and meta-analysis on the use of human platelet lysate for mesenchymal stem cell cultures: comparison with fetal bovine serum and considerations on the production protocol

Mesenchymal stem cell (MSC) culturing for cell therapies needs a step forward to be routinely used in clinical settings. Main concerns regard the use of animal origin reagents, in particular supplementing the culture medium with FBS. Lately, Human Platelet Lysate (HPL) has been proposed as animal-fr...

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Detalles Bibliográficos
Autores principales: Palombella, Silvia, Perucca Orfei, Carlotta, Castellini, Greta, Gianola, Silvia, Lopa, Silvia, Mastrogiacomo, Maddalena, Moretti, Matteo, de Girolamo, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981660/
https://www.ncbi.nlm.nih.gov/pubmed/35379348
http://dx.doi.org/10.1186/s13287-022-02815-1