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Modeling the syn-cycle in the light activated opening of the channelrhodopsin-2 ion channel

The ion channel of channelrhodopsin-2 (ChR2) is activated by absorbing light. The light stimulates retinal to isomerize to start the photocycle. There are two pathways for photocycles, which are caused by isomerization of the retinal from all-trans, 15-anti to 13-cis, 15-anti in the dark-adapted sta...

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Detalles Bibliográficos
Autores principales: Xin, Qi, Cheng, Jie, Wang, Hongwei, Zhang, Wenying, Lu, Hong, Zhou, Junpeng, Lo, Glenn V., Dou, Yusheng, Yuan, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981705/
https://www.ncbi.nlm.nih.gov/pubmed/35424642
http://dx.doi.org/10.1039/d1ra08521b