Recruitment of α4β7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behavior

BACKGROUND: Behavioral comorbidities, such as anxiety and depression, are a prominent feature of IBD. The signals from the inflamed gut that cause changes in the brain leading to these behavioral comorbidities remain to be fully elucidated. We tested the hypothesis that enhanced leukocyte–cerebral e...

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Detalles Bibliográficos
Autores principales: Cluny, Nina L., Nyuyki, Kewir D., Almishri, Wagdi, Griffin, Lateece, Lee, Benjamin H., Hirota, Simon A., Pittman, Quentin J., Swain, Mark G., Sharkey, Keith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981853/
https://www.ncbi.nlm.nih.gov/pubmed/35379260
http://dx.doi.org/10.1186/s12974-022-02431-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981853/
https://www.ncbi.nlm.nih.gov/pubmed/35379260
http://dx.doi.org/10.1186/s12974-022-02431-z

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