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Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells

Radio-chemotherapy with 5-flu orouracil (5-FU) is the standard of care treatment for patients with colorectal cancer, but it is only effective for a third of them. Despite our understanding of the mechanism of action of 5-FU, drug resistance remains a significant limitation to the clinical use of 5-...

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Detalles Bibliográficos
Autores principales: Chauvin, Anaïs, Bergeron, Danny, Vencic, Jean, Lévesque, Dominique, Paquette, Benoit, Scott, Michelle S., Boisvert, François-Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981854/
https://www.ncbi.nlm.nih.gov/pubmed/35379199
http://dx.doi.org/10.1186/s12885-022-09417-3