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Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells
Radio-chemotherapy with 5-flu orouracil (5-FU) is the standard of care treatment for patients with colorectal cancer, but it is only effective for a third of them. Despite our understanding of the mechanism of action of 5-FU, drug resistance remains a significant limitation to the clinical use of 5-...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981854/ https://www.ncbi.nlm.nih.gov/pubmed/35379199 http://dx.doi.org/10.1186/s12885-022-09417-3 |