Cargando…

Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells

Radio-chemotherapy with 5-flu orouracil (5-FU) is the standard of care treatment for patients with colorectal cancer, but it is only effective for a third of them. Despite our understanding of the mechanism of action of 5-FU, drug resistance remains a significant limitation to the clinical use of 5-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chauvin, Anaïs, Bergeron, Danny, Vencic, Jean, Lévesque, Dominique, Paquette, Benoit, Scott, Michelle S., Boisvert, François-Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981854/ https://www.ncbi.nlm.nih.gov/pubmed/35379199 http://dx.doi.org/10.1186/s12885-022-09417-3

Ejemplares similares

Zinc Fingers Function Cooperatively with KRAB Domain for Nuclear Localization of KRAB-Containing Zinc Finger Proteins
por: Wang, Wei, et al.
Publicado: (2014)

KRAB-containing zinc-finger repressor proteins
por: Urrutia, Raul
Publicado: (2003)

Evolving imprinting control regions: KRAB zinc fingers hold the key
por: Juan, Aimee M., et al.
Publicado: (2019)

Genetic features and genomic targets of human KRAB-zinc finger proteins
por: de Tribolet-Hardy, Jonas, et al.
Publicado: (2023)

The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification
por: Helleboid, Pierre‐Yves, et al.
Publicado: (2019)

KRAB zinc finger protein diversification drives mammalian interindividual methylation variability
por: Bertozzi, Tessa M., et al.
Publicado: (2020)

KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions
por: Lupo, Angelo, et al.
Publicado: (2013)

KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage
por: Wolf, Gernot, et al.
Publicado: (2020)

Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression
por: Ito, Jumpei, et al.
Publicado: (2020)

Structural Evolution of Gene Promoters Driven by Primate-Specific KRAB Zinc Finger Proteins
por: Farmiloe, Grace, et al.
Publicado: (2023)

The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons
por: Seah, Michelle K. Y., et al.
Publicado: (2019)

The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses
por: Wolf, Gernot, et al.
Publicado: (2015)

KRAB-zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptomes and genome evolution
por: Otsuka, Kai, et al.
Publicado: (2023)

Quantifying the arms race between LINE-1 and KRAB-zinc finger genes through TECookbook
por: Zuo, Zheng
Publicado: (2023)

The Transcriptional Repressive Activity of KRAB Zinc Finger Proteins Does Not Correlate with Their Ability to Recruit TRIM28
por: Murphy, Kristin E., et al.
Publicado: (2016)

Primate-restricted KRAB zinc finger proteins and target retrotransposons control gene expression in human neurons
por: Turelli, Priscilla, et al.
Publicado: (2020)

Mutant KRAS regulates transposable element RNA and innate immunity via KRAB zinc-finger genes
por: Reggiardo, Roman E., et al.
Publicado: (2022)

An evolutionary arms race between KRAB zinc finger genes 91/93 and SVA/L1 retrotransposons
por: Jacobs, Frank MJ, et al.
Publicado: (2014)

The mouse genome displays highly dynamic populations of KRAB-zinc finger protein genes and related genetic units
por: Kauzlaric, Annamaria, et al.
Publicado: (2017)

Clinical Proteomics in Colorectal Cancer, a Promising Tool for Improving Personalised Medicine
por: Chauvin, Anaïs, et al.
Publicado: (2018)

Myocardial ischemic preconditioning upregulated protein 1(Mipu1):zinc finger protein 667 - a multifunctional KRAB/C(2)H(2) zinc finger protein
por: Han, D., et al.
Publicado: (2014)

KRAB–Zinc Finger Proteins and KAP1 Can Mediate Long-Range Transcriptional Repression through Heterochromatin Spreading
por: Groner, Anna C., et al.
Publicado: (2010)

The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability
por: Ho, Teresa L.F., et al.
Publicado: (2016)

KRAB-type zinc-finger proteins PITA and PISA specifically regulate p53-dependent glycolysis and mitochondrial respiration
por: Wang, Shan, et al.
Publicado: (2018)

Role of the Transcriptional Repressor Zinc Finger with KRAB and SCAN Domains 3 (ZKSCAN3) in Retinal Pigment Epithelial Cells
por: Pan, Hsuan-Yeh, et al.
Publicado: (2021)

KRAB zinc finger protein ZNF676 controls the transcriptional influence of LTR12-related endogenous retrovirus sequences
por: Iouranova, Alexandra, et al.
Publicado: (2022)

MAGE I Transcription Factors Regulate KAP1 and KRAB Domain Zinc Finger Transcription Factor Mediated Gene Repression
por: Xiao, Tony Z., et al.
Publicado: (2011)

The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances
por: Monteagudo-Sánchez, Ana, et al.
Publicado: (2020)

Conserved paradoxical relationships among the evolutionary, structural and expressional features of KRAB zinc-finger proteins reveal their special functional characteristics
por: Shen, Pan, et al.
Publicado: (2021)

Comparison of ChIP-Seq Data and a Reference Motif Set for Human KRAB C2H2 Zinc Finger Proteins
por: Barazandeh, Marjan, et al.
Publicado: (2017)

KRAB-Zinc Finger Protein ZNF268a Deficiency Attenuates the Virus-Induced Pro-Inflammatory Response by Preventing IKK Complex Assembly
por: Liu, Yi, et al.
Publicado: (2019)

Protein interaction network of alternatively spliced NudCD1 isoforms
por: Asselin-Mullen, Patrick, et al.
Publicado: (2017)

Destabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks
por: Drissi, Romain, et al.
Publicado: (2018)

The response to neoadjuvant chemoradiotherapy with 5-fluorouracil in locally advanced rectal cancer patients: a predictive proteomic signature
por: Chauvin, Anaïs, et al.
Publicado: (2018)

KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer
por: Pei, Lijiao, et al.
Publicado: (2018)

ZNF91 deletion in human embryonic stem cells leads to ectopic activation of SVA retrotransposons and up-regulation of KRAB zinc finger gene clusters
por: Haring, Nina L., et al.
Publicado: (2021)

The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues
por: Lorenz, Peter, et al.
Publicado: (2010)

Downregulation of CacyBP by CRISPR/dCas9-KRAB Prevents Bladder Cancer Progression
por: Zheng, Hanxiong, et al.
Publicado: (2021)

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells
por: Chang, Yao-Jen, et al.
Publicado: (2023)

ZFP92, a KRAB domain zinc finger protein enriched in pancreatic islets, binds to B1/Alu SINE transposable elements and regulates retroelements and genes
por: Osipovich, Anna B., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0niah4nrj6n01rv75s93qf9rvi