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Uncovering the Quantitative Relationships Among Chromosome Fluctuations, Epigenetics, and Gene Expressions of Transdifferentiation on Waddington Landscape

The 3D spatial organization of the chromosomes appears to be linked to the gene function, which is cell type‐specific. The chromosome structural ensemble switching model (CSESM) is developed by employing a heteropolymer model on different cell types and the important quantitative relationships among...

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Detalles Bibliográficos
Autores principales: Chu, Wen‐Ting, Chu, Xiakun, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981899/
https://www.ncbi.nlm.nih.gov/pubmed/35104056
http://dx.doi.org/10.1002/advs.202103617