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Quantifying Cell‐Derived Changes in Collagen Synthesis, Alignment, and Mechanics in a 3D Connective Tissue Model

Dysregulation of extracellular matrix (ECM) synthesis, organization, and mechanics are hallmark features of diseases like fibrosis and cancer. However, most in vitro models fail to recapitulate the three‐dimensional (3D) multi‐scale hierarchical architecture of collagen‐rich tissues and as a result,...

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Detalles Bibliográficos
Autores principales: Wilks, Benjamin T., Evans, Elisabeth B., Howes, Andrew, Hopkins, Caitlin M., Nakhla, Morcos N., Williams, Geoffrey, Morgan, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981917/
https://www.ncbi.nlm.nih.gov/pubmed/35102708
http://dx.doi.org/10.1002/advs.202103939