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Quantifying Cell‐Derived Changes in Collagen Synthesis, Alignment, and Mechanics in a 3D Connective Tissue Model
Dysregulation of extracellular matrix (ECM) synthesis, organization, and mechanics are hallmark features of diseases like fibrosis and cancer. However, most in vitro models fail to recapitulate the three‐dimensional (3D) multi‐scale hierarchical architecture of collagen‐rich tissues and as a result,...
Autores principales: | Wilks, Benjamin T., Evans, Elisabeth B., Howes, Andrew, Hopkins, Caitlin M., Nakhla, Morcos N., Williams, Geoffrey, Morgan, Jeffrey R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981917/ https://www.ncbi.nlm.nih.gov/pubmed/35102708 http://dx.doi.org/10.1002/advs.202103939 |
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