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Haplotype-based inference of the distribution of fitness effects

Recent genome sequencing studies with large sample sizes in humans have discovered a vast quantity of low-frequency variants, providing an important source of information to analyze how selection is acting on human genetic variation. In order to estimate the strength of natural selection acting on l...

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Detalles Bibliográficos
Autores principales: Ortega-Del Vecchyo, Diego, Lohmueller, Kirk E, Novembre, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982047/
https://www.ncbi.nlm.nih.gov/pubmed/35100400
http://dx.doi.org/10.1093/genetics/iyac002