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Study of the Pauson–Khand reaction in flow over alkynylphenyl vinyl ethers: towards the synthesis of tricyclic multisubstituted benzofurans

The use of flow methodology allows the use of alkynylphenyl vinyl ethers (benzo-fused 1,7 enynes) as substrates for the intramolecular Pauson–Khand reaction (PKr). Forced temperature and pressure conditions during a short reaction time minimize the substrate decomposition allowing the formation of t...

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Detalles Bibliográficos
Autores principales: García-Lacuna, Jorge, Alonso, Maialen, Domínguez, Gema, Pérez Castells, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982164/
https://www.ncbi.nlm.nih.gov/pubmed/35424686
http://dx.doi.org/10.1039/d2ra01062c