Significant structural change in human c-Myc promoter G-quadruplex upon peptide binding in potassium

We selected the G-quadruplex motif located in the nuclease-hypersensitive elements (NHE) III1 region of the c-Myc promoter and for the first time performed its interaction studies with a designed peptide (QW10). Our CD results showed that the peptide bound to the c-Myc G-quadruplex and induced a sig...

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Detalles Bibliográficos
Autores principales: Kundu, Nikita, Sharma, Taniya, Kaur, Sarvpreet, Singh, Mamta, Kumar, Vinit, Sharma, Uttam, Jain, Aklank, Shankaraswamy, Jadala, Miyoshi, Daisuke, Saxena, Sarika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982240/
https://www.ncbi.nlm.nih.gov/pubmed/35424772
http://dx.doi.org/10.1039/d2ra00535b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982240/
https://www.ncbi.nlm.nih.gov/pubmed/35424772
http://dx.doi.org/10.1039/d2ra00535b

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