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Preclinical evaluation of drug treatment options for sleep‐related epileptiform spiking in Alzheimer's disease

INTRODUCTION: There are no published data on prospective clinical studies on drug treatment options for sleep‐related epileptiform spiking in Alzheimer's disease (AD). METHODS: Using video‐EEG with hippocampal electrodes in 17 APP/PS1 transgenic male mice we assessed the effects of donepezil an...

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Detalles Bibliográficos
Autores principales: Jin, Nanxiang, Gureviciene, Irina, Atalay, Aysu Naz, Häkli, Sara, Ziyatdinova, Sofya, Tanila, Heikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982322/
https://www.ncbi.nlm.nih.gov/pubmed/35415205
http://dx.doi.org/10.1002/trc2.12291