Encapsulating Cas9 into extracellular vesicles by protein myristoylation

CRISPR/Cas9 genome editing is a very promising avenue for the treatment of a variety of genetic diseases. However, it is still very challenging to encapsulate CRISPR/Cas9 machinery for delivery. Protein N‐myristoylation is an irreversible co/post‐translational modification that results in the covale...

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Detalles Bibliográficos
Autores principales: Whitley, Joseph Andrew, Kim, Sungjin, Lou, Lei, Ye, Chenming, Alsaidan, Omar Awad, Sulejmani, Essilvo, Cai, Jingwen, Desrochers, Ellison Gerona, Beharry, Zanna, Rickman, Catherine Bowes, Klingeborn, Mikael, Liu, Yutao, Xie, Zhong‐Ru, Cai, Houjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982324/
https://www.ncbi.nlm.nih.gov/pubmed/35384352
http://dx.doi.org/10.1002/jev2.12196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982324/
https://www.ncbi.nlm.nih.gov/pubmed/35384352
http://dx.doi.org/10.1002/jev2.12196

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