Cargando…

Encapsulating Cas9 into extracellular vesicles by protein myristoylation

CRISPR/Cas9 genome editing is a very promising avenue for the treatment of a variety of genetic diseases. However, it is still very challenging to encapsulate CRISPR/Cas9 machinery for delivery. Protein N‐myristoylation is an irreversible co/post‐translational modification that results in the covale...

Descripción completa

Detalles Bibliográficos
Autores principales:	Whitley, Joseph Andrew, Kim, Sungjin, Lou, Lei, Ye, Chenming, Alsaidan, Omar Awad, Sulejmani, Essilvo, Cai, Jingwen, Desrochers, Ellison Gerona, Beharry, Zanna, Rickman, Catherine Bowes, Klingeborn, Mikael, Liu, Yutao, Xie, Zhong‐Ru, Cai, Houjian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982324/ https://www.ncbi.nlm.nih.gov/pubmed/35384352 http://dx.doi.org/10.1002/jev2.12196

Ejemplares similares

Targeting protein myristoylation for the treatment of prostate cancer
por: Sulejmani, Essilvo, et al.
Publicado: (2018)

Paracrine Fibroblast Growth Factor Initiates Oncogenic Synergy with Epithelial FGFR/Src Transformation in Prostate Tumor Progression()()
por: Li, Qianjin, et al.
Publicado: (2018)

Author Correction: Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers
por: Klingeborn, Mikael, et al.
Publicado: (2018)

Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice
por: Landowski, Michael, et al.
Publicado: (2019)

Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers
por: Klingeborn, Mikael, et al.
Publicado: (2017)

Engineering extracellular vesicles to deliver CRISPR ribonucleoprotein for gene editing
por: Whitley, Joseph Andrew, et al.
Publicado: (2023)

Myristoylation versus SRP
por: LeBrasseur, Nicole
Publicado: (2005)

Data on the calcium-induced mobility shift of myristoylated and non-myristoylated forms of neurocalcin delta
por: Viviano, Jeffrey, et al.
Publicado: (2016)

MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins
por: Maurer-Stroh, Sebastian, et al.
Publicado: (2004)

Profiling of myristoylation in Toxoplasma gondii reveals an N-myristoylated protein important for host cell penetration
por: Broncel, Malgorzata, et al.
Publicado: (2020)

Design and Characterization of Myristoylated and Non-Myristoylated Peptides Effective against Candida spp. Clinical Isolates
por: Bugli, Francesca, et al.
Publicado: (2022)

Long chain fatty acyl-CoA synthetase 1 promotes prostate cancer progression by elevation of lipogenesis and fatty acid beta-oxidation
por: Ma, Yongjie, et al.
Publicado: (2021)

AAV Gene Augmentation of Truncated Complement Factor H Differentially Rescues Ocular Complement Dysregulation in a Mouse Model
por: Grigsby, Daniel, et al.
Publicado: (2023)

Myristoylation profiling in human cells and zebrafish
por: Broncel, Malgorzata, et al.
Publicado: (2015)

Protein Lipidation by Palmitoylation and Myristoylation in Cancer
por: Fhu, Chee Wai, et al.
Publicado: (2021)

Prediction of N-myristoylation modification of proteins by SVM
por: Cao, Wei, et al.
Publicado: (2011)

Myristoylation: An Important Protein Modification in the Immune Response
por: Udenwobele, Daniel Ikenna, et al.
Publicado: (2017)

Predicting N-terminal myristoylation sites in plant proteins
por: Podell, Sheila, et al.
Publicado: (2004)

Data on the identity and myristoylation state of recombinant, purified hippocalcin
por: Krishnan, Anuradha, et al.
Publicado: (2016)

Targeting N-myristoylation for therapy of B-cell lymphomas
por: Beauchamp, Erwan, et al.
Publicado: (2020)

N-myristoylation: from cell biology to translational medicine
por: Yuan, Meng, et al.
Publicado: (2020)

Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration
por: Toomey, Christopher B., et al.
Publicado: (2018)

Myristoylated CIL-7 regulates ciliary extracellular vesicle biogenesis
por: Maguire, Julie E., et al.
Publicado: (2015)

Myristoyl group-aided protein import into the mitochondrial intermembrane space
por: Ueda, Eri, et al.
Publicado: (2019)

Protein N-myristoylation: functions and mechanisms in control of innate immunity
por: Wang, Bin, et al.
Publicado: (2021)

Bringing the Ca(2+) sensitivity of myristoylated recoverin into the physiological range
por: Marino, Valerio, et al.
Publicado: (2021)

The role of lysine palmitoylation/myristoylation in the function of the TEAD transcription factors
por: Mesrouze, Yannick, et al.
Publicado: (2022)

Lipidation Alters the Structure and Hydration of Myristoylated Intrinsically Disordered Proteins
por: Ji, Jingjing, et al.
Publicado: (2023)

Myristoyl’s dual role in allosterically regulating and localizing Abl kinase
por: de Buhr, Svenja, et al.
Publicado: (2023)

Application of Liquid-Liquid Extraction for N-terminal Myristoylation Proteomics
por: Tsumagari, Kazuya, et al.
Publicado: (2023)

Targeting Lipid Metabolism for the Treatment of Age-Related Macular Degeneration: Insights from Preclinical Mouse Models
por: Landowski, Michael, et al.
Publicado: (2022)

The role of myristoylation in the membrane association of the Lassa virus matrix protein Z
por: Strecker, Thomas, et al.
Publicado: (2006)

Fatty acids impact sarcomere integrity through myristoylation and ER homeostasis
por: Tang, Hongyun, et al.
Publicado: (2021)

Single Vector System for Efficient N-myristoylation of Recombinant Proteins in E. coli
por: Glück, Julian M., et al.
Publicado: (2010)

Global profiling of co- and post-translationally N-myristoylated proteomes in human cells
por: Thinon, Emmanuelle, et al.
Publicado: (2014)

Cellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated Proteins
por: Najumudeen, Arafath Kaja, et al.
Publicado: (2013)

Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex
por: Morita, Daisuke, et al.
Publicado: (2016)

Myristoylation drives dimerization of matrix protein from mouse mammary tumor virus
por: Doležal, Michal, et al.
Publicado: (2016)

N‐Lauroylation during the Expression of Recombinant N‐Myristoylated Proteins: Implications and Solutions
por: Flamm, Andrea Gabriele, et al.
Publicado: (2015)

A metabolic labeling protocol to enrich myristoylated proteins from Caenorhabditis elegans
por: Gong, Xin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ut4ea8bibh7mot8m1a7dhg1ntd