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Asymmetric total synthesis of (1S,2S,4S)-β-elemene

Elemenes are sesquiterpene natural products extracted from Chinese medicinal herbs and have been used as an important antitumor drug in China. Here, we report the first stereoselective total synthesis of (1S,2S,4S)-β-elemene using (R)-carvone as a chiral pool starting material. The isopropenyl moiet...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Feng, Zhun, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982354/
https://www.ncbi.nlm.nih.gov/pubmed/35424753
http://dx.doi.org/10.1039/d2ra01408d