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Sequential stabilization of RNF220 by RLIM and ZC4H2 during cerebellum development and Shh-group medulloblastoma progression

Sonic hedgehog (Shh) signaling is essential for the proliferation of cerebellar granule neuron progenitors (CGNPs), and its misregulation is linked to various disorders, including cerebellar cancer medulloblastoma (MB). During vertebrate neural development, RNF220, a ubiquitin E3 ligase, is involved...

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Detalles Bibliográficos
Autores principales: Li, Yuwei, Yang, Chencheng, Wang, Huishan, Zhao, Ling, Kong, Qinghua, Cang, Yu, Zhao, Shuhua, Lv, Longbao, Li, Yan, Mao, Bingyu, Ma, Pengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982406/
https://www.ncbi.nlm.nih.gov/pubmed/35040952
http://dx.doi.org/10.1093/jmcb/mjab082