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Identification of novel furo[2,3-d]pyrimidine based chalcones as potent anti-breast cancer agents: synthesis, in vitro and in vivo biological evaluation

Various substituted synthetic chalcones demonstrated potent anti-cancer activities. In the current study a series of novel furo[2,3-d]pyrimidine based chalcones were synthesized as potential anticancer agents. Among the different substituted derivatives, two of the halogen bearing chalcones, 5d and...

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Detalles Bibliográficos
Autores principales: Mansour, Mai A., Oraby, Mamdouh A., Muhammad, Zeinab A., Lasheen, Deena S., Gaber, Hatem M., Abouzid, Khaled A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982411/
https://www.ncbi.nlm.nih.gov/pubmed/35424720
http://dx.doi.org/10.1039/d2ra00889k