PNA microprobe for label-free detection of expanded trinucleotide repeats

We present a PNA microprobe sensing platform to detect trinucleotide repeat mutation by electrochemical impedance spectroscopy. The microprobe platform discriminated Huntington's disease-associated CAG repeats in cell-derived total RNA with S/N 1 : 3. This sensitive, label-free, and PCR-free de...

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Detalles Bibliográficos
Autores principales: Asefifeyzabadi, Narges, Durocher, Grace, Tshilenge, Kizito-Tshitoko, Alam, Tanimul, Ellerby, Lisa M., Shamsi, Mohtashim H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982460/
https://www.ncbi.nlm.nih.gov/pubmed/35424746
http://dx.doi.org/10.1039/d2ra00230b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982460/
https://www.ncbi.nlm.nih.gov/pubmed/35424746
http://dx.doi.org/10.1039/d2ra00230b

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