SCAI promotes error‐free repair of DNA interstrand crosslinks via the Fanconi anemia pathway

DNA interstrand crosslinks (ICLs) are cytotoxic lesions that threaten genome integrity. The Fanconi anemia (FA) pathway orchestrates ICL repair during DNA replication, with ubiquitylated FANCI‐FANCD2 (ID2) marking the activation step that triggers incisions on DNA to unhook the ICL. Restoration of i...

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Detalles Bibliográficos
Autores principales: Schubert, Lisa, Hendriks, Ivo A, Hertz, Emil P T, Wu, Wei, Sellés‐Baiget, Selene, Hoffmann, Saskia, Viswalingam, Keerthana Stine, Gallina, Irene, Pentakota, Satyakrishna, Benedict, Bente, Johansen, Joachim, Apelt, Katja, Luijsterburg, Martijn S, Rasmussen, Simon, Lisby, Michael, Liu, Ying, Nielsen, Michael L, Mailand, Niels, Duxin, Julien P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982572/
https://www.ncbi.nlm.nih.gov/pubmed/35156773
http://dx.doi.org/10.15252/embr.202153639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982572/
https://www.ncbi.nlm.nih.gov/pubmed/35156773
http://dx.doi.org/10.15252/embr.202153639

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