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miR‐AB, a miRNA‐based shRNA viral toolkit for multicolor‐barcoded multiplex RNAi at a single‐cell level

Uncovering the functions of genes in a complex biological process is fundamental for systems biology. However, currently there is no simple and reliable experimental tool available to conduct loss‐of‐function experiments for multiple genes in every possible combination in a single experiment, which...

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Detalles Bibliográficos
Autores principales: Wang, Dapeng, Xiu, Jianbo, Zhao, Jiangyue, Luo, Junli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982575/
https://www.ncbi.nlm.nih.gov/pubmed/35201651
http://dx.doi.org/10.15252/embr.202153691