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Epigenetic inheritance is gated by naïve pluripotency and Dppa2

Environmental factors can trigger cellular responses that propagate across mitosis or even generations. Perturbations to the epigenome could underpin such acquired changes, however, the extent and contexts in which modified chromatin states confer heritable memory in mammals is unclear. Here, we exp...

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Detalles Bibliográficos
Autores principales: Carlini, Valentina, Policarpi, Cristina, Hackett, Jamie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982627/
https://www.ncbi.nlm.nih.gov/pubmed/35199868
http://dx.doi.org/10.15252/embj.2021108677