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Regression discontinuity analysis for pharmacovigilance: statin example reflected trial findings showing little evidence of harm

OBJECTIVES: The study aims to explore the use of regression discontinuity analysis (RDA) to examine effects of prescription of statins on total cholesterol and adverse outcomes (type 2 diabetes, rhabdomyolysis and myopathy, myalgia and myositis, liver disease, CVD, and mortality). STUDY DESIGN AND S...

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Detalles Bibliográficos
Autores principales: Scott, Lauren, Redaniel, Maria Theresa, Booker, Matthew, Payne, Rupert A., Tilling, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982642/
https://www.ncbi.nlm.nih.gov/pubmed/34648942
http://dx.doi.org/10.1016/j.jclinepi.2021.10.003