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A small molecule, C(24)H(17)ClN(4)O(2)S, inhibits the function of the type III secretion system in Salmonella Typhimurium

BACKGROUND: Salmonella enterica serovar Typhimurium (S. Typhimurium) causes gastroenteritis and diarrhea in humans and food-producing animals. The type III secretion system (T3SS) has been known to be a potent virulence mechanism by injecting effector proteins into the cytosol of host cells. S. Typh...

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Detalles Bibliográficos
Autores principales: Boonyom, Rerngwit, Roytrakul, Sittiruk, Thinwang, Patipat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982747/
https://www.ncbi.nlm.nih.gov/pubmed/35380331
http://dx.doi.org/10.1186/s43141-022-00336-1