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An ensemble of parameters from a robust Markov-based model reproduces L-type calcium currents from different human cardiac myocytes
The development of modeling structures at the channel level that can integrate subcellular and cell models and properly reproduce different experimental data is of utmost importance in cardiac electrophysiology. In contrast to gate-based models, Markov Chain models are well suited to promote the int...
Autores principales: | Novaes, Gustavo Montes, Alvarez-Lacalle, Enrique, Muñoz, Sergio Alonso, dos Santos, Rodrigo Weber |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982880/ https://www.ncbi.nlm.nih.gov/pubmed/35381041 http://dx.doi.org/10.1371/journal.pone.0266233 |
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