Newcastle disease virus expressing an angiogenic inhibitor exerts an enhanced therapeutic efficacy in colon cancer model

Newcastle disease virus (NDV)-mediated gene therapy is a promising new approach for treatment of cancer but shows limited anti-angiogenesis. VEGF-Trap plays a vital role in anti-angiogenesis. To enhance the anti-tumor effect of NDV, VEGF-Trap gene was incorporated into the genome of rNDV in this stu...

Descripción completa

Detalles Bibliográficos
Autores principales: Meng, Fanrui, Cao, Yukai, Su, Han, Liu, Tianyan, Tian, Limin, Zhang, Yu, Yang, Jiarui, Xiao, Wei, Li, Deshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982889/
https://www.ncbi.nlm.nih.gov/pubmed/35381011
http://dx.doi.org/10.1371/journal.pone.0264896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982889/
https://www.ncbi.nlm.nih.gov/pubmed/35381011
http://dx.doi.org/10.1371/journal.pone.0264896

Ejemplares similares