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Newcastle disease virus expressing an angiogenic inhibitor exerts an enhanced therapeutic efficacy in colon cancer model

Newcastle disease virus (NDV)-mediated gene therapy is a promising new approach for treatment of cancer but shows limited anti-angiogenesis. VEGF-Trap plays a vital role in anti-angiogenesis. To enhance the anti-tumor effect of NDV, VEGF-Trap gene was incorporated into the genome of rNDV in this stu...

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Detalles Bibliográficos
Autores principales:	Meng, Fanrui, Cao, Yukai, Su, Han, Liu, Tianyan, Tian, Limin, Zhang, Yu, Yang, Jiarui, Xiao, Wei, Li, Deshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982889/ https://www.ncbi.nlm.nih.gov/pubmed/35381011 http://dx.doi.org/10.1371/journal.pone.0264896

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