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A novel network based linear model for prioritization of synergistic drug combinations

Drug combination therapies can improve drug efficacy, reduce drug dosage, and overcome drug resistance in cancer treatments. Current research strategies to determine which drug combinations have a synergistic effect rely mainly on clinical or empirical experience and screening predefined pools of dr...

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Detalles Bibliográficos
Autores principales: Li, Jiaqi, Xu, Hongyan, McIndoe, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982899/
https://www.ncbi.nlm.nih.gov/pubmed/35381038
http://dx.doi.org/10.1371/journal.pone.0266382