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In silico discovery of non-psychoactive scaffolds in Cannabis halting SARS-CoV-2 host entry and replication machinery

Aim: Coronavirus disease still poses a global health threat which advocates continuous research efforts to develop effective therapeutics. Materials & methods: We screened out an array of 29 cannabis phytoligands for their viral spike-ACE2 complex and main protease (M(pro)) inhibitory actions by...

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Detalles Bibliográficos
Autores principales: Khattab, Amira R, Teleb, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982993/
https://www.ncbi.nlm.nih.gov/pubmed/35399958
http://dx.doi.org/10.2217/fvl-2021-0309