Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy

Abundant filamentous inclusions of tau are characteristic of more than 20 neurodegenerative diseases that are collectively termed tauopathies. Electron cryo-microscopy (cryo-EM) structures of tau amyloid filaments from human brain revealed that distinct tau folds characterise many different diseases...

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Detalles Bibliográficos
Autores principales: Lövestam, Sofia, Koh, Fujiet Adrian, van Knippenberg, Bart, Kotecha, Abhay, Murzin, Alexey G, Goedert, Michel, Scheres, Sjors HW
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983045/
https://www.ncbi.nlm.nih.gov/pubmed/35244536
http://dx.doi.org/10.7554/eLife.76494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983045/
https://www.ncbi.nlm.nih.gov/pubmed/35244536
http://dx.doi.org/10.7554/eLife.76494

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