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Cell-surface tethered promiscuous biotinylators enable comparative small-scale surface proteomic analysis of human extracellular vesicles and cells

Characterization of cell surface proteome differences between cancer and healthy cells is a valuable approach for the identification of novel diagnostic and therapeutic targets. However, selective sampling of surface proteins for proteomics requires large samples (>10e6 cells) and long labeling t...

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Detalles Bibliográficos
Autores principales: Kirkemo, Lisa L, Elledge, Susanna K, Yang, Jiuling, Byrnes, James R, Glasgow, Jeff E, Blelloch, Robert, Wells, James A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983049/
https://www.ncbi.nlm.nih.gov/pubmed/35257663
http://dx.doi.org/10.7554/eLife.73982