Maladaptive functional changes in alveolar fibroblasts due to perinatal hyperoxia impair epithelial differentiation

Infants born prematurely worldwide have up to a 50% chance of developing bronchopulmonary dysplasia (BPD), a clinical morbidity characterized by dysregulated lung alveolarization and microvascular development. It is known that PDGFR alpha–positive (PDGFRA(+)) fibroblasts are critical for alveolariza...

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Detalles Bibliográficos
Autores principales: Riccetti, Matthew R., Ushakumary, Mereena George, Waltamath, Marion, Green, Jenna, Snowball, John, Dautel, Sydney E., Endale, Mehari, Lami, Bonny, Woods, Jason, Ahlfeld, Shawn K., Perl, Anne-Karina T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983125/
https://www.ncbi.nlm.nih.gov/pubmed/35113810
http://dx.doi.org/10.1172/jci.insight.152404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983125/
https://www.ncbi.nlm.nih.gov/pubmed/35113810
http://dx.doi.org/10.1172/jci.insight.152404

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